A 53-year-old motorcyclist is in hospital with life-threatening injuries after a collision with another vehicle on Highway 401 in Mississauga Monday afternoon.

Ontario Provincial Police responded to the crash in the eastbound express lanes near Winston Churchill Boulevard around 4 p.m. The motorcyclist was taken to hospital in serious condition.

The eastbound express lanes were closed between Winston Churchill Boulevard and Mavis Road while police investigated the collision. The investigation remains ongoing.