A three-vehicle collision on Highway 401 in Woodstock caused a major disruption Friday morning, forcing the closure of all eastbound lanes for several hours.

Ontario Provincial Police say the crash occurred around 4 a.m. and involved a box truck, a transport truck and a passenger vehicle. The driver of the passenger vehicle suffered serious but non-life-threatening injuries, while both truck drivers escaped unharmed.

One of the trucks was carrying a full load and overturned onto its side. Crews had to remove the cargo by hand as part of the recovery operation.

The eastbound lanes were closed between Highway 2 and Oxford Road 29 before reopening around noon.

The investigation remains ongoing, and police had not announced any charges yet.