A fatal multi-vehicle collision shut down the QEW in both directions in Niagara Falls on Wednesday afternoon.

The crash occurred around 2:45 p.m. between Thorold Stone Road and Mountain Road, involving two passenger vehicles and a tractor-trailer. The transport truck came to rest across the highway and became entangled with a large overhead sign on the Niagara-bound side.

Police confirmed the tractor-trailer driver, a 48-year-old Barrie man, died at the scene. A female driver was airlifted to a trauma centre with life-threatening injuries, while the third driver was unharmed.

The investigation and highway cleanup took considerable time, with the highway reopening at approximately 6 a.m. Thursday morning.

No charges have been laid as of yet. The cause of the collision remains under investigation.